Controlled Substances, Precursor Chemicals & Apparatus

Image of tableting machine, a regulated laboratory apparatus


The Texas Higher Education Coordinating Board has entered into a memorandum of understanding (MOU) with the Texas Department of Public Safety (TX DPS) regarding the control of certain controlled substances, precursor chemicals, and laboratory apparatus used at the University.  Furthermore, Federal Regulations restrict the use of certain controlled substances at the University. The University will maintain strict accountability of all such “Regulated Items” as described below.

Regulated Items

“Regulated Items” include the five categories of controlled substances, chemicals and laboratory apparatus listed below.

Controlled Substances

All substances, including drugs, adulterants and dilutants as defined by the Health and Safety Code, Chapter 481, the Texas Controlled Substances Act and Title 21 United States Code (USC), Subchapter I, Part A, the USC Controlled Substances Act.  The current TX DPS list of controlled substances can be found at and the current USC list of controlled substance can be found at

Controlled Substance Analogues

  1. All substances with a chemical structure substantially similar to the chemical structure of a controlled substance in Schedule I or II or Penalty Group 1, 1-A, or 2 of the Texas Health and Safety Code, Chapter 481, Texas Controlled Substances Act; and
  2. All substances specifically designed to produce an effect substantially similar to, or greater than, the effect of a controlled substance in Schedule I or II or Penalty Group 1, 1-A, or 2 of the Texas Health and Safety Code, Chapter 481, Texas Controlled Substances Act.

Precursor Chemicals

  1. Methylamine
  2. Ethylamine
  3. D-Lysergic Acid
  4. Ergotamine Tartrate
  5. Diethyl Malonate
  6. Malonic Acid
  7. Ethyl Malonate
  8. Barbituric Acid
  9. Piperidine
  10. N-Acetylanthranilic Acid
  11. Pyrrolidine
  12. Phenylacetic Acid
  13. Anthranilic Acid
  14. Hypophosphorus Acid
  15. Ephedrine
  16. Pseudoephedrine
  17. Norpseudoephedrine
  18. Phenylpropanolamine
  19. Red Phosphorus

Immediate Precursors

  1. Benzaldehyde
  2. Gamma-Butyrolactone (other names include: GBL; Dihydro-2(3H)-furanone; 1,2-Butanolide; 1,4-Butanolide; 4-Hydroxybutanoic acid lactone; gamma-hydroxybutyric acid lactone)
  3. Isosafrole
  4. 3,4-Methylenedioxyphenyl-2 propanone
  5. N-Methylephedrine, its salts, optical isomers, and salts of optical isomers
  6. N-Methylpseudoephedrine, its salts, optical isomers, and salts of optical isomers
  7. Piperonal
  8. Safrol
  9. Lithium metal removed from a battery and immersed in kerosene, mineral spirits, or similar liquid that prevents or retards hydration

Laboratory Apparatus

  1. Condensers
  2. Distilling Apparatus
  3. Vacuum Dryers
  4. Distilling Flasks
  5. Florence Flasks
  6. Single, Two, and Three-Necked Flasks
  7. Erlenmeyer Flasks
  8. Thermometer Flasks
  9. Round-Bottom Flasks
  10. Filtering Flasks
  11. Tableting Machines
  12. Encapsulating Machines
  13. Filter Funnels
  14. Buchner Funnels
  15. Separatory Funnels
  16. Soxhlet Extractors
  17. Transformers
  18. Flask Heaters
  19. Heating Mantles
  20. Adapter Tubes

 Please see the Regulated Laboratory Apparatus Visual Guide for examples of regulated laboratory apparatus. 


Principal users include any Principal Investigator, Laboratory Supervisor, Chairperson, or other person in charge of spaces where regulated items are present.


  1. All principal investigators who desire to purchase, possess, or use controlled substances (Schedules I-V) for laboratory research must register and maintain active registration with the Federal Drug Enforcement Administration (DEA). Further information on registering with the DEA can be found at
  2. Each principal user of Regulated Items, including apparatuses, is required to keep adequate usage records of those items. Such records may include copies of purchase order records, an annual inventory, and any other documentation necessary to detect loss, pilferage, or theft. Copies of such records may be requested by TX DPS, and they must be provided within 10 business days of the request.
  3. Each laboratory or storage area where Regulated Items are located must be provided with appropriate security by principal users. This will generally require storage areas to be locked when not attended by TWU faculty or staff or other appropriate designated personnel.
  4. Any unusual or unexplained discrepancy, loss, pilferage, or theft of a Regulated Item will be immediately reported by the principal user to TWU Risk Management and the TWU Department of Public Safety (TWU DPS). TWU DPS will act as the investigating agency as per the MOU, with the assistance of TX DPS upon request. A written report of the incident must be submitted to TX DPS within 5 business days.
  5. Regulated Items will not be sold or transferred to any person or entity not holding a DPS permit, unless the recipient is specifically exempted by law or rule.
    1. Educational or research programs of a school district or a public or private institution of higher education are exempt from obtaining a TX DPS permit.
    2. Any sale or transfer of Regulated Items (including surplus property) to authorized persons must be reported to TX DPS within 30 days using TX DPS form NAR-22. The original form must be mailed to TX DPS, and a copy must be maintained on site for a minimum of 2 years. Contact Risk Management prior to any sale or off-site transfer of Regulated Items so the appropriate forms can be obtained.
  6. Disposal of Regulated Items will be accomplished through TWU waste disposal procedures as appropriate (e.g. disposal of controlled substances, controlled substance analogues, and precursor chemicals shall be through the TWU Regulated Waste Disposal procedure).
  7. Risk Management will review storage and security of Regulated Items during routine laboratory inspections.
  8. Annually, TWU Risk Management shall provide TX DPS a list of individuals who are responsible for implementing security measures related to Regulated Items. Listed individuals shall serve as the points of contact between TWU and the TX DPS.

Page last updated 11:43 AM, June 1, 2022