Michael Bergel, Ph.D.

Contact

mbergel@twu.edu
940-898-2471
GRB 223

Education

Ph.D., Cancer Biology, Cytogenetics and Molecular Genetics, The Hebrew University of Jerusalem, Israel
M.S., Genetics, The Hebrew University of Jerusalem, Israel
B.S., Biology, The Hebrew University of Jerusalem, Israel

Research Interests

Molecular Biology; Cell Biology; Genetics; Chromatin Remodeling in Cellular Stress Response; Cancer

Latest Articles

Mitotic activation of a novel histone deacetylase 3-linker histone H1.3 complex by protein kinase CK2
The Journal of Biological Chemistry (2015)
Hemangi Patil, Carrie Wilks, Rhiannon Wold Gonzalez, Sudheer Dhanireddy, Heather Conrad-Webb

Current Projects

My research is directed towards identifying novel chromatin-associated targets for cancer therapy and cancer prevention. The lab studies the cellular response to stresses (such as UV irradiation) and particularly focuses on the chromatin remodeling level. The rationale is that understanding the mechanism, by which our cells repair DNA-damage caused by ultraviolet irradiation, can help in developing a more efficient generation of sunscreens. Other projects in my lab focus on developing new anti-cancer drugs that target the function of chromatin and chromosomes. We also study the involvement of complexes of chromatin modifying enzymes in the division of chromosomes during Mitosis.

Externally Funded Projects

Chromatin condensation as a DNA protective response to UV radiation in human melanocytes and aging C. elegans
National Institute of Health | $131,000.00 | 2018
Role: Co-Principal Investigator

Internally Funded Projects

Testing the Anti-Cancer Efficacy and Mechanism of Action of Novel Amidoximes in a Mouse Breast Cancer Pre-Clinical Study
GOV-Texas Woman's University | $10,000.00 | 2018
Research Grant

New Investigator Research Enhancement Program (REP) Grant
2017
Research Grant

Exploring Chromatin Compaction and DNA Protection Following UV-Irradiation by Utilizing a Direct Live Cell Imaging Approach and Physiological Conditions
GOV-Texas Woman's University | $10,000.00 | 2015
Research Grant

Professional Affiliations

• American Society for Biochemistry and Molecular Biology
• Distinguished Member, National Society of Collegiate Scholars (NSCS)
• Member of the Texas Society for Microscopy
• Sigma Xi, The Scientific Research Society