2016 News Releases

Biology team’s cancer cell research appears on cover of The Journal of Biological Chemistry

Photo of Michael Bergel

Research led by associate biology professor Michael Bergel appears on the cover of The Journal of Biological Chemistry. Photo by Michael Modecki

Research identifying a new protein complex associated with cell division, led by Texas Woman’s University associate biology professor Michael Bergel, is featured on the cover of the Feb. 12 issue of The Journal of Biological Chemistry.

“Using immunofluorescence staining of the cells, along with other molecular techniques, helped my research team to identify a novel protein complex with an unusual location within the cell,” said Bergel, Ph.D. “This complex appears to be involved in the cell’s division, therefore it is a genuine target for cancer therapy.”

Bergel continued, “By identifying this complex, we eventually can work to stop the cancerous process or identify more effective ways of treating these cancer cells.” 

Co-authoring the article —  “Mitotic Activation of a Novel Histone Deacetylase 3-Linker Histone H1.3 Complex by Protein Kinase CK2” — along with Bergel are TWU alumna Hemangi Patil, Ph.D., a faculty member at Valencia College in Orlando; alumnus Sudheer Dhanireddy, Ph.D., a senior clinical trial analyst for Parexel, Inc; TWU biology doctoral candidates Carrie Wilks and Rhiannon Wold Gonzalez; and TWU associate biology professor Heather Conrad-Webb, Ph.D.

Feb. 12, 2016 Journal of Biological Chemistry cover

TWU biology doctoral candidate Sanil Sansar designed the cover image used by the publication.

“Having TWU research featured on the cover of this prestigious and well-known journal speaks to the national significance of TWU’s Biology Department,” Bergel said. “Our department is doing important and meaningful research work in various fields of cell signaling, including cancer research, and we are looking forward to continued progress and breakthroughs.”

The complete article can be found at: www.jbc.org/content/early/2015/12/09/jbc.M115.643874. This article was made openly available to all by the TWU Open Access Fund. The fund was setup by university Academic Affairs and managed by the library to promote open access by making research more accessible and to promote new modes of scholarly communication.

Bergel has been a member of the faculty of the TWU Biology Department since 2003. He was a postdoctoral fellow at the National Institutes of Health, National Cancer Institute and earned his Ph.D., master’s and bachelor’s degrees from  The Hebrew University of Jerusalem.

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