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Christopher S. Brower

Chris Brower

Assistant Professor
PO Box 425799
Texas Woman's University
Denton, TX 76204-5799

Office Location: GRB 323
Office Phone: 940-898-2706
Lab Phone:
Fax: 940-898-2382

Teaching Area: Molecular Biology, Cell Biology, Genetics
Research Area: Gene Regulation, Protein Modification, Protein Degradation


Position Date Institution Field
Postdoc 2001-2007 California Institute of Technology Biology
Ph.D. 1998-2001 University of Oklahoma Health Science Ctr. Biochemistry & Molecular Biology
M.S. 1996-1998 University of Oklahoma Health Science Ctr. Biochemistry & Molecular Biology
B.S. 1990-1994 Northeastern Oklahoma State University Biology

Major Academic/Research Interest


My broad scientific interests include the ubiquitin proteasome system and how proteolytic degradation contributes to cellular biology, mammalian physiology, and human disease.

Project List

Select Publications

  • Brower C.S., Piatkov K., and Varshavsky A. (2013) Neurodegeneration-Associated Protein Fragments As Short-Lived Substrates of the N-End Rule Pathway.Molecular Cell, 50:161-71.
  • Piatkov K.I.*, Brower C.S.* and Alexander Varshavsky (2012) The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments. Proc. Natl. Acad. Sci. USA. PMID: 22670058.* Equal contribution.
  • Brower C.S., Veiga, L., Jones, R.H., Varshavsky A. (2010) Mouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcription. J Biol Chem.285:17218-34.

Courses and Teaching Responsibilities


Project List

page last updated 1/3/2017 2:15 PM